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Mephedrone also inhibited the two synaptosomal DA and 5HT uptake. Like methylenedioxymethamphetamine, but contrary to methamphetamine or methcathinone, repeated mephedrone administrations also brought on persistent serotonergic, although not dopaminergic, deficits. On the other hand, mephedrone triggered DA launch from a striatal suspension approac

The drug or automobile was administered at time 0 min (arrow). Recurring steps two-way anova accompanied by Bonferroni put up-take a look at; the drug-taken care of groups were being when compared With all the car or truck group: amphetamine: aaaHe mentioned the decision by the Home Secretary was "unduly determined by media and political pressure"